From Risk Of Coma And Amputation To Successful Recovery: Hyperbaric Oxygen Therapy Saves The Day

Apr 01, 2026

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Uncle Tian, 57, was admitted to the hospital due to acute carbon monoxide poisoning, coma, swelling and cyanosis of his right lower leg. This led to crush syndrome, rhabdomyolysis, acute renal failure, and his right lower leg was at risk of amputation.

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Immediately after admission, he received treatments including blood purification, internal environment stabilization, and hyperbaric oxygen therapy. After 34 days of emergency treatment, he was discharged smoothly.
During his stay, multiple consultations with hand and foot surgeons were arranged, and three general anesthesia surgeries were successfully performed:
• Fasciotomy and decompression of the right lower leg
• Debridement with VSD negative pressure drainage
• Skin grafting
He also received hyperbaric oxygen therapy 30 times simultaneously, with remarkable curative effects:
• Full recovery of consciousness
• Restoration of renal function
• Survival of the transplanted skin flap on the right lower leg
• Avoidance of amputation


1. Severe limb compression can cause crush syndrome and rhabdomyolysis, leading to acute renal failure, arrhythmia, and even death.
2. Hyperbaric oxygen serves as an adjuvant therapy for rhabdomyolysis, improving blood circulation in the necrotic lower leg, enabling surgical intervention, preserving the limb, and preventing amputation.
3. Therapeutic Mechanism:
Hyperbaric oxygen increases oxygen diffusion distance and oxygen content, promoting angiogenesis and the formation of collateral circulation. It improves ischemia and hypoxia in wounds, accelerates granulation tissue growth and collagen fiber formation, speeds up wound healing, enhances the survival rate of transplanted skin flaps, and reduces hypertrophic scarring.